phenobarbital will decrease the extent or influence of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Powerful or moderate CYP3A4 inducers may maximize rate of diazepam elimination; thus, efficacy of diazepam might be diminished.Observe Intently (1)somatropin will lower the level or effect of phenobar